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Denali Therapeutics Inc (DNLI) Stock Price
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DNLI Stock Price & Analysis — Denali Therapeutics Inc (Healthcare >> Biotechnology)

DNLI FAQ

What is DNLI's ROE?

Denali Therapeutics Inc reports a Return on Equity (ROE) of -54.86%.

What is DNLI's dividend yield?

Denali Therapeutics Inc offers a dividend yield of 0.00%.

What is DNLI's Quality Score?

Our AI rates DNLI's overall financial quality at 23 out of 100, based on profitability, growth, debt and earnings stability.

Is now a good time to buy DNLI?

Our AI Timing Score for DNLI is 67 out of 100, indicating the relative attractiveness of buying at the current price using technical and momentum signals.

Which sector does DNLI belong to?

Denali Therapeutics Inc is classified under the Healthcare >> Biotechnology sector on the NASDAQ exchange

Stock Check   *Daily update data at 8:30 AM*
(Price: 2026-08-03 | FS: 2026-03-31)

DNLI AI Analysis Summary

Our AI summary for DNLI: Denali Therapeutics Inc (NASDAQ), Healthcare >> Biotechnology sector. The stock currently trades at a P/E of 0.00, ROE of -54.86%, a dividend yield of 0.00%. Its financial Quality Score stands at 23/100 — fundamentals below the market average. The AI Timing Score is 67/100 — technical signals are mixed; watch for a clearer trend. All scores are recomputed automatically after each market close from official exchange data. This is systematically generated analysis, not personalized investment advice.

DNLI

Denali Therapeutics Inc
USD 23.15
0.13 (0.56%) Day Change
0.01
D/E
-54.9%
ROE
-40.1%
ROA
0.00%
Div Yield
USD 23.15
Price
0.13 (0.56%)
Day Change
NEWS SCORE: 89

DNLI, the overall quality is not good ( Quality = 23) and the timing to buy is ...(Sign In to See)...

23

QUALITY

Signal
UNDERPERFORM
Signal Description
Company financial health is Not Good
Reason
ROE is relatively low.
ROA is relatively low.
Historical ROE is relatively low
Negative growth of ROE in the last year.
ROE is decreasing significantly
ROA is too relatively low compare to ROE
Growth of ROA was below our criteria in the last year.
Net profit margin is relatively low.
Acceleration of net profit margin growth rate is below our criteria
Historical net profit margin is relatively low.

88 Sign in

TIMING

Signal
OUTPERFORM
Signal Descri...
Good
Reason
Momentum indicators aligned on the daily timeframe
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In details, quality factors are not good , financial health is not quite good , and ability to make profit is not good , ...

Quality Factors 45%
X
X
X
X
  In Recommendations? Not in any sections
  Select Rate 0.00 From 30 days period
  Watch Rate 0.00 From 30 days period
  News Score 89
  Magic Formula Rank by ROA
N/A
  Magic Formula Rank by ROE
N/A
  Magic Formula Rank by ROIC
N/A
  Price 23.15
  PBV / Sector
3.95 / 44,219.29
  Earning Per Share -3.22
  PE / Sector
N/A / 19.28
  PEG or PE/Growth / Sector
N/A / 1.23
  Average 1M Daily Value
40.54 M
GREAT
  Average 1W Daily Value
34.05 M
GREAT
Timing Factors 28%
  MACD
  MACD Signal
  MACD Divergence
  RSI
  Stochastic Oscillator K
  Stochastic Oscillator D
  ADX
  Avg 5 day Timing Score
Financial Health 50%
X
X
X
X
  DE / Sector
  DE Average / Sector
  DE Change Average (%) / Sector
  Current Ratio / Sector
  Current Ratio Average / Sector
  Current Ratio Change Average (%) / Sector
  Quick Ratio / Sector
  Quick Ratio Average / Sector
  Quick Ratio Change Average (%) / Sector
  FCF/Share / Sector
  FCF/Share Average / Sector
  FCF/Share Change Average (%) / Sector
Ability to Make Profit 47%
X
X
X
X
X
X
X
  GPM (%) / Sector
  GPM Average (%) / Sector
  GPM Change Average (%) / Sector
  OPM (%) / Sector
  OPM Average (%) / Sector
  OPM Change Average (%) / Sector
  NPM (%) / Sector
N/A / 98.22
  NPM Average (%) / Sector
-172.25 / -1,697.63
  NPM Change Average (%) / Sector
N/A / 5,097.97
  Asset Turnover / Sector
  Asset Turnover Average / Sector
  Asset Turnover Change Average (%) / Sector
  ROA (%) / Sector
-40.13 / 185,260.96
  ROA Average (%) / Sector
-30.11 / 36,684.70
  ROA Change Average (%) / Sector
33.99 / 422,221.66
GREAT
  ROE (%) / Sector
-54.86 / 243,762.23
  ROE Average (%) / Sector
-37.03 / 48,758.47
  ROE Change Average (%) / Sector
36.17 / 424,968.10
GREAT
  ROIC (%) / Sector
  ROIC Average (%) / Sector
  ROIC Change Average (%) / Sector
Return to Investors 4%
X
  Dividend (%) / Sector
N/A / 0.04
  Dividend Average (%) / Sector
N/A / 17.04
  Dividend Change Average (%) / Sector
N/A / -0.19
Registration Details
X
  Analyze Date 2026-08-04 08:01:24
  Symbol DNLI
  Name DENALI THERAPEUTICS INC
  Sector Healthcare >> Biotechnology
  Market NASDAQ
  Listed Shares 158.71 M
  Par Value N/A
  Calculated From Quarter
  Sign N/A
  Market Cap (M.USD) / Sector Average 3,653.50 / 9,645.64
News, Concensus, ...
  Estimation Consensus See at WSJ.com
  Full details See at WSJ.com
  Chart See in Chart feature
  News See at Yahoo Finance

Address: 161 Oyster Point Boulevard, South San Francisco, CA, United States, 94080

Phone: 650 866 8547

Website: https://www.denalitherapeutics.com

Employees: 507

Sector: Healthcare >> Biotechnology

Description: Denali Therapeutics Inc., a biopharmaceutical company, discovers and develops therapeutics to treat neurodegenerative and lysosomal storage diseases. The company develops Eclitasertib (SAR443122/DNL758) RIPK1 inhibitor program for peripheral inflammatory diseases; BIIB122/DNL151 LRRK2 inhibitor program for Parkinson's disease; TAK-594/DNL593 program for frontotemporal dementia-granulin; DNL126 program for MPS IIIA (Sanfilippo Syndrome A); and DNL310 Tividenofusp alfa, an enzyme replacement therapy program for MPS II (Hunter Syndrome). Its Enzyme TransportVehicle (TV) programs include DNL952 for the treatment of Pompe disease; DNL111 for Parkinson's and Gaucher diseases; and DNL622 for Hurler syndrome (MPS I). The company's OTV programs also comprise DNL628 targeting tau for Alzheimer's disease; and DNL422 targeting alpha synuclein for Parkinson's disease, as well as antibody TV program includes DNL921 targeting Abeta for treating Alzheimer's disease. The company was formerly known as SPR Pharma Inc. and changed its name to Denali Therapeutics Inc. in March 2015. Denali Therapeutics Inc. was incorporated in 2013 and is headquartered in South San Francisco, California.

Analyst Ratings & Target Price

3 Months Ago
1 Month Ago
Current
Strong Buy
15
15
15
Buy
4
4
4
Hold
0
0
0
Sell
0
0
0
Strong Sell
0
0
0
Consensus
Strong Buy 4.79
Strong Buy 4.79
Strong Buy 4.79
Target Price
USD 35.64
USD 33.93
USD 34.31

Per-Share Earnings, Estimates vs Actuals

Actual
Analyst Range
Estimate

ME vs SECTOR Healthcare >> Biotechnology

DNLI (ME)
Sector Peers
Bubble size = Market Cap

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Stocks in the Same Sector

Healthcare › Biotechnology

Analysed on the same criteria, ordered by market cap

News

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DNLI
DNLI
USD 23.15 (0.56%)
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