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Karyopharm Therapeutics Inc (KPTI) Stock Price
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KPTI Stock Price & Analysis — Karyopharm Therapeutics Inc (Healthcare >> Biotechnology)

KPTI FAQ

What is KPTI's ROE?

Karyopharm Therapeutics Inc reports a Return on Equity (ROE) of 73.39%.

What is KPTI's dividend yield?

Karyopharm Therapeutics Inc offers a dividend yield of 0.00%.

What is KPTI's Quality Score?

Our AI rates KPTI's overall financial quality at 54 out of 100, based on profitability, growth, debt and earnings stability.

Is now a good time to buy KPTI?

Our AI Timing Score for KPTI is 26 out of 100, indicating the relative attractiveness of buying at the current price using technical and momentum signals.

Which sector does KPTI belong to?

Karyopharm Therapeutics Inc is classified under the Healthcare >> Biotechnology sector on the NASDAQ exchange

Stock Check   *Daily update data at 8:30 AM*
(Price: 2026-08-03 | FS: 2026-03-31)

KPTI AI Analysis Summary

Our AI summary for KPTI: Karyopharm Therapeutics Inc (NASDAQ), Healthcare >> Biotechnology sector. The stock currently trades at a P/E of 0.00, ROE of 73.39%, a dividend yield of 0.00%. Its financial Quality Score stands at 54/100 — mid-range fundamentals relative to the market. The AI Timing Score is 26/100 — most technical signals do not support an entry at this point. All scores are recomputed automatically after each market close from official exchange data. This is systematically generated analysis, not personalized investment advice.

KPTI

Karyopharm Therapeutics Inc
US:NASDAQ STOCK Healthcare >> Biotechnology
USD 1.97
0.05 (2.60%) Day Change
-0.85
D/E
73.4%
ROE
-148.4%
ROA
0.00%
Div Yield

KARYOPHARM THERAPEUTICS INC
TYPE: STOCK
MARKET: NASDAQ

Compare   Watchlist   Myport
USD 1.97
Price
0.05 (2.60%)
Day Change
NEWS SCORE: N/A

KPTI, the overall quality is not quite good ( Quality = 54) and the timing to buy is ...(Sign In to See)...

54

QUALITY

Signal
UNDERPERFORM
Signal Description
Company financial health is Not Good
Reason
ROA is relatively low.
Acceleration of ROE growth rate is below our criteria.
ROA is too relatively low compare to ROE
Growth of ROA was below our criteria in the last year.
Net profit margin is relatively low.
Historical net profit margin is relatively low.

88 Sign in

TIMING

Signal
OUTPERFORM
Signal Descri...
Good
Reason
Momentum indicators aligned on the daily timeframe
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In details, quality factors are not good , financial health is not good , and ability to make profit is ok , ...

Quality Factors 48%
X
X
X
X
  In Recommendations? Not in any sections
  Select Rate 0.00 From 30 days period
  Watch Rate 0.00 From 30 days period
  News Score N/A
  Magic Formula Rank by ROA
N/A
  Magic Formula Rank by ROE
N/A
  Magic Formula Rank by ROIC
N/A
  Price 1.97
  PBV / Sector
-0.16 / 44,219.29
  Earning Per Share -8.83
  PE / Sector
N/A / 19.28
  PEG or PE/Growth / Sector
N/A / 1.23
  Average 1M Daily Value
7.00 M
  Average 1W Daily Value
12.47 M
GREAT
Timing Factors 28%
  MACD
  MACD Signal
  MACD Divergence
  RSI
  Stochastic Oscillator K
  Stochastic Oscillator D
  ADX
  Avg 5 day Timing Score
Financial Health 37%
X
X
X
X
  DE / Sector
  DE Average / Sector
  DE Change Average (%) / Sector
  Current Ratio / Sector
  Current Ratio Average / Sector
  Current Ratio Change Average (%) / Sector
  Quick Ratio / Sector
  Quick Ratio Average / Sector
  Quick Ratio Change Average (%) / Sector
  FCF/Share / Sector
  FCF/Share Average / Sector
  FCF/Share Change Average (%) / Sector
Ability to Make Profit 60%
X
X
X
X
X
X
X
  GPM (%) / Sector
  GPM Average (%) / Sector
  GPM Change Average (%) / Sector
  OPM (%) / Sector
  OPM Average (%) / Sector
  OPM Change Average (%) / Sector
  NPM (%) / Sector
-129.02 / 98.22
  NPM Average (%) / Sector
-103.81 / -1,697.63
  NPM Change Average (%) / Sector
24.50 / 5,097.97
GREAT
  Asset Turnover / Sector
  Asset Turnover Average / Sector
  Asset Turnover Change Average (%) / Sector
  ROA (%) / Sector
-148.36 / 185,260.96
  ROA Average (%) / Sector
-96.27 / 36,684.70
  ROA Change Average (%) / Sector
69.53 / 422,221.66
GREAT
  ROE (%) / Sector
73.39 / 243,762.23
GREAT
  ROE Average (%) / Sector
255.77 / 48,758.47
GREAT
  ROE Change Average (%) / Sector
-19.44 / 424,968.10
  ROIC (%) / Sector
  ROIC Average (%) / Sector
  ROIC Change Average (%) / Sector
Return to Investors 4%
X
  Dividend (%) / Sector
N/A / 0.04
  Dividend Average (%) / Sector
N/A / 17.04
  Dividend Change Average (%) / Sector
N/A / -0.19
Registration Details
X
  Analyze Date 2026-08-04 08:01:46
  Symbol KPTI
  Name KARYOPHARM THERAPEUTICS INC
  Sector Healthcare >> Biotechnology
  Market NASDAQ
  Listed Shares 22.66 M
  Par Value N/A
  Calculated From Quarter
  Sign N/A
  Market Cap (M.USD) / Sector Average 43.51 / 9,645.64
News, Concensus, ...
  Estimation Consensus See at WSJ.com
  Full details See at WSJ.com
  Chart See in Chart feature
  News See at Yahoo Finance

Address: 85 Wells Avenue, Newton, MA, United States, 02459-3298

Phone: 617 658 0600

Website: https://www.karyopharm.com

Employees: 228

Sector: Healthcare >> Biotechnology

Description: Karyopharm Therapeutics Inc., a commercial-stage pharmaceutical company, discovers, develops, and commercializes drugs directed against nuclear export for the treatment of cancer and other diseases in the United States. The company discovers, develops, and commercializes novel and small molecule Selective Inhibitor of Nuclear Export (SINE) compounds that inhibit the nuclear export protein exportin 1 (XPO1). Its lead compounds include XPOVIO in combination with bortezomib and dexamethasone for the treatment of adult patients with multiple myeloma; in combination with dexamethasone for the treatment of adult patients with relapsed or refractory multiple myeloma; and for the treatment of adult patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL). It also develops Selinexor for treating hematological and solid tumor malignancies, including multiple myeloma, endometrial cancer, myelofibrosis, and DLBCL; and ELTANEXOR for treating other myeloproliferative neoplasms and TP53 wild-type solid tumors. In addition, the company has license agreement with Menarini Group to develop and commercialize selinexor for human oncology indications; license agreement with Antengene Therapeutics Limited to develop and commercialize selinexor, eltanexor, and KPT-9274 for the treatment and/or prevention of human oncology indications, as well as verdinexor for the diagnosis, treatment, and/or prevention of human non-oncology indications; and distribution agreement for the commercialization of XPOVIO with FORUS Therapeutics Inc. Further, the company has a collaboration with Bristol Myers Squibb company to evaluate novel cereblon E3 ligase modulator agent mezigdomide in combination with Selinexor in patients with relapsed or refractory multiple myeloma. Karyopharm Therapeutics Inc. was incorporated in 2008 and is headquartered in Newton, Massachusetts.

Analyst Ratings & Target Price

3 Months Ago
1 Month Ago
Current
Strong Buy
2
4
4
Buy
3
2
2
Hold
1
1
1
Sell
0
0
0
Strong Sell
0
0
0
Consensus
Buy 4.17
Buy 4.43
Buy 4.43
Target Price
USD 12.33
USD 13.50
USD 8.67

Per-Share Earnings, Estimates vs Actuals

Actual
Analyst Range
Estimate

ME vs SECTOR Healthcare >> Biotechnology

KPTI (ME)
Sector Peers
Bubble size = Market Cap

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Stocks in the Same Sector

Healthcare › Biotechnology

Analysed on the same criteria, ordered by market cap

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KPTI
KPTI
USD 1.97 (2.60%)
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