Top movers analysis in the middle of the day on 2025-08-21: top gainers and losers in today's session.

Let's have a look at what is happening on the US markets in the middle of the day on Thursday. Below you can find the top gainers and losers in today's session.

[topmovers]

GAINERS

TICKER
CHANGE
COMMENT

PTIX [https://www.chartmill.com/stock/quote/PTIX/profile]
102.0%
Investors witnessed a remarkable 102.0% rise in PROTAGENIC THERAPEUTICS INC'S (NASDAQ:PTIX [https://www.chartmill.com/stock/quote/PTIX/profile]) shares, which climbed to $4.6 during Thursday's session. In the last month the share price dropped with 32.34%.

AEMD [https://www.chartmill.com/stock/quote/AEMD/profile]
54.95%
AETHLON MEDICAL INC (NASDAQ:AEMD [https://www.chartmill.com/stock/quote/AEMD/profile]) experienced a significant 54.95% increase, reaching $1.72 during Thursday's session. The stock is trading 20.71% lower than a month ago.

SLQT [https://www.chartmill.com/stock/quote/SLQT/profile]
38.52%
Exciting news for SELECTQUOTE INC (NYSE:SLQT [https://www.chartmill.com/stock/quote/SLQT/profile]) as its stock price surged 38.52% to $2.54 during Thursday's session. The company's earnings where released Yesterday. A press release (INVESTOR ALERT: Pomerantz Law Firm Reminds Investors with Losses on their Investment in SelectQuote, Inc. of Class Action Lawsuit and Upcoming Deadlines - SLQT [https://www.chartmill.com/news/SLQT/gnwcq-2025-8-21-investor-alert-pomerantz-law-firm-reminds-investors-with-losses-on-their-investment-in-selectquote-inc-of-class-action-lawsuit-and-upcoming-deadlines-slqt]) was released earlier today.

THAR [https://www.chartmill.com/stock/quote/THAR/profile]
35.7%
THARIMMUNE INC (NASDAQ:THAR [https://www.chartmill.com/stock/quote/THAR/profile]) experienced a significant 35.7% increase, reaching $4.87 during Thursday's session. A press release (Tharimmune Reports Pharmacokinetic Simulation Results for TH104 as Prophylaxis Against Respiratory Depression from Fentanyl and Ultrapotent Opioids, Highlighting Potential Superiority Over Existing Treatments [https://www.chartmill.com/news/THAR/accwirecq-2025-8-20-tharimmune-reports-pharmacokinetic-simulation-results-for-th104-as-prophylaxis-against-respiratory-depression-from-fentanyl-and-ultrapotent-opioids-highlighting-potential-superiority-over-existing-treatments]) was released yesterday.

CUPR [https://www.chartmill.com/stock/quote/CUPR/profile]
28.57%
Investors celebrated as CUPRINA HOLDINGS CAYMAN-A (NASDAQ:CUPR [https://www.chartmill.com/stock/quote/CUPR/profile]) experienced a 28.57% rise in its shares, closing at $1.08 during Thursday's session. In the last month the stock lost 89.16%.

IMRX [https://www.chartmill.com/stock/quote/IMRX/profile]
26.67%
IMMUNEERING CORP - CLASS A (NASDAQ:IMRX [https://www.chartmill.com/stock/quote/IMRX/profile]) experienced a significant 26.67% increase, reaching $4.34 during Thursday's session. In the last 3 months the share price increased with 123.0%.

FLYE [https://www.chartmill.com/stock/quote/FLYE/profile]
25.62%
FLY-E GROUP INC'S (NASDAQ:FLYE [https://www.chartmill.com/stock/quote/FLYE/profile]) stock price is advancing with 25.62% to a price of $0.76. The stock is trading 88.45% lower than a month ago.

STSS [https://www.chartmill.com/stock/quote/STSS/profile]
22.24%
SHARPS TECHNOLOGY INC'S (NASDAQ:STSS [https://www.chartmill.com/stock/quote/STSS/profile]) stock price displayed strong growth, advancing 22.24% and reaching $5.92 during Thursday's session. Shareholders saw the stock price going 23.17% lower in the past month.

APUS [https://www.chartmill.com/stock/quote/APUS/profile]
21.55%
In an impressive move, APIMEDS PHARMACEUTICALS US I'S (NYSEARCA:APUS [https://www.chartmill.com/stock/quote/APUS/profile]) shares recorded a 21.55% increase, closing at $2.2 during Thursday's session.

STAK [https://www.chartmill.com/stock/quote/STAK/profile]
20.98%
STAK INC-A'S (NASDAQ:STAK [https://www.chartmill.com/stock/quote/STAK/profile]) stock price increased by 20.98% to $1.73. In the last month the share price dropped with 24.74%.

To see the full list of top gainers you can use our top gainers [https://www.chartmill.com/stock/market/top-gainers-and-losers/usa-nyse-nasdaq-amex] page.

LOSERS

TICKER
CHANGE
COMMENT

MODV [https://www.chartmill.com/stock/quote/MODV/profile]
-62.87%
MODIVCARE INC'S (NASDAQ:MODV [https://www.chartmill.com/stock/quote/MODV/profile]) shares fell 62.87% to $0.69. Yesterday the company had a press release: Modivcare Enters into Comprehensive Restructuring Agreement to Strengthen its Future, Reduce Debt and Inject Capital [https://www.chartmill.com/news/MODV/bizwire-2025-8-21-modivcare-enters-into-comprehensive-restructuring-agreement-to-strengthen-its-future-reduce-debt-and-inject-capital].

STFS [https://www.chartmill.com/stock/quote/STFS/profile]
-55.89%
STAR FASHION CULTURE HLDG-A'S (NASDAQ:STFS [https://www.chartmill.com/stock/quote/STFS/profile]) stock price encountered a 55.89% decline, reaching $0.19 during Thursday's session. In the last month the stock lost 75.56%.

GWAV [https://www.chartmill.com/stock/quote/GWAV/profile]
-46.53%
GREENWAVE TECHNOLOGY SOLUTIO'S (NASDAQ:GWAV [https://www.chartmill.com/stock/quote/GWAV/profile]) stock price decreased by 46.53% to $0.09. In the last month the share price dropped with 42.86%.

QH [https://www.chartmill.com/stock/quote/QH/profile]
-37.61%
QUHUO LTD-ADR'S (NASDAQ:QH [https://www.chartmill.com/stock/quote/QH/profile]) stock price faced a 37.61% decline, reaching $0.06 during Thursday's session. In the last month the share price dropped with 93.6%.

SUGP [https://www.chartmill.com/stock/quote/SUGP/profile]
-31.05%
SU GROUP HOLDINGS LTD'S (NASDAQ:SUGP [https://www.chartmill.com/stock/quote/SUGP/profile]) shares fell 31.05% to $0.4 during Thursday's session. In the last month the stock lost 22.72%.

RMSG [https://www.chartmill.com/stock/quote/RMSG/profile]
-27.64%
REAL MESSENGER CORP'S (NASDAQ:RMSG [https://www.chartmill.com/stock/quote/RMSG/profile]) stock price decreased by 27.64% to $3.77. Shareholders saw the stock price going 126.0% higher in the past month.

ZYBT [https://www.chartmill.com/stock/quote/ZYBT/profile]
-26.12%
ZHENGYE BIOTECHNOLOGY HOLDIN'S (NASDAQ:ZYBT [https://www.chartmill.com/stock/quote/ZYBT/profile]) stock price decreased by 26.12% to $7.01. In the last month the stock gained 64.19%.

DFLIW [https://www.chartmill.com/stock/quote/DFLIW/profile]
-22.37%
The market experienced a downward movement in CHARDAN NEXTECH ACQUISI-CW27'S (NASDAQ:DFLIW [https://www.chartmill.com/stock/quote/DFLIW/profile]) stock price, closing at $0.04 with a 22.37% decrease during Thursday's session. The stock is trading 27.4% higher than a month ago.

NVNO [https://www.chartmill.com/stock/quote/NVNO/profile]
-20.37%
ENVVENO MEDICAL CORP'S (NASDAQ:NVNO [https://www.chartmill.com/stock/quote/NVNO/profile]) stock price encountered a 20.37% decline, reaching $0.93 during Thursday's session. A press release (enVVeno Receives Not-Approvable Letter from the FDA for the VenoValve(R) [https://www.chartmill.com/news/NVNO/accwirecq-2025-8-20-envveno-receives-not-approvable-letter-from-the-fda-for-the-venovalver]) was released yesterday.

COTY [https://www.chartmill.com/stock/quote/COTY/profile]
-20.06%
COTY INC-CL A'S (NYSE:COTY [https://www.chartmill.com/stock/quote/COTY/profile]) shares fell 20.06% to $3.88 during Thursday's session. A press release (Coty Reports FY25 and Q4 Results; Targets Sequential LFL and EBITDA Trend Improvement in FY26, Returning to Growth in 2H26 [https://www.chartmill.com/news/COTY/bizwire-2025-8-20-coty-reports-fy25-and-q4-results-targets-sequential-lfl-and-ebitda-trend-improvement-in-fy26-returning-to-growth-in-2h26]) was released yesterday.

For the full top loser list go to our top losers [https://www.chartmill.com/stock/market/top-gainers-and-losers/usa-nyse-nasdaq-amex] page.